Abbott, global health care company, is all set to preview the m2000, its new real-time PCR automated molecular diagnostic system, at the annual American Association for Clinical Chemistry (AACC) meeting in Chicago (July 23-27). Edward Michael, president of Abbott Molecular, said: The m2000 has been designed to help our customers deliver patient test results quickly and efficiently, with extremely accurate results. This innovative system represents our continued commitment to accelerate automation for the clinical molecular laboratory and improve the diagnosis, monitoring and care of patients with infectious diseases and other serious illnesses. The m2000 system comprises two instruments: the Abbott m2000sp and the m2000rt. It links an automated sample preparation instrument (m2000sp) with an integrated real-time PCR amplification and detection instrument (m2000rt) via software to provide automation from sample extraction to the reporting of the final test result. The robotic arm of m2000 eliminates steps such as manual pipetting, reducing hands-on time required to prepare samples for DNA/RNA testing by as much as 75 percent.
Everything in the medical gadgets world is undergoing significant changes and transformation whether we take the example of the new Implanon or the Rheo Knee. Now, it’s the turn of DNA. The researchers claim that they have found a second code in DNA in addition to the genetic code. Eran Segal of the Weizmann Institute in Israel and Jonathan Widom of Northwestern University in Illinois and their colleagues describe the new code in the current issue of Nature. The genetic code specifies all the proteins that a cell makes. The second code, superimposed on the first, sets the placement of the nucleosomes, miniature protein spools around which the DNA is looped. The spools both protect and control access to the DNA itself. What the researchers claim, if confirmed, could open new insights into the higher order control of the genes, like the critical but still mysterious process by which each type of human cell is allowed to activate the genes it needs but cannot access the genes used by other types of cell.
Now, testing for deadly pathogens in food, air and water will no more be a cumbersome and expensive affair. A Michigan State University researcher and his team have made it easier with their new device – it is portable and hand-held device that can detect up to 50 microbial threat agents in air, water and food! That sounds interesting! This hand-held ‘all-in-one pathogen testing center’ can amplify DNA and identify pathogen on the same DNA biochip – having a signature pieces of DNA attached to a silica surface that is similar to a computer chip. The biochip is about the size of a thumbnail. Syed Hashsham, an associate professor in the Department of Civil and Environmental Engineering and the Center for Microbial Ecology said, This device will give us the ability to measure pathogens in a manner and at a price that really matters for human health. If we can screen for all pathogens together, we can minimize the threat significantly.
To analyze your DNA in the comfort of your home, Spartan Bioscience Incorporation has announced the commercial launch of their Spartan DXTM real-time PCR (polymerase chain reaction) DNA analyzer. This highly accurate DNA testing device is a ‘gold standard’ for molecular diagnostics that promises to offer DNA results in just 30 minutes or less for 4 samples at a time. Though, it is a bit slow and expensive, since batched in contrast to mainframe-style DNA machines those are especially designed for highly-trained scientists to work on high-throughput environments and if we compare this machine with other mainframe-style DNA machines, Spartan DXTM is designed for non-batched, on-demand DNA applications in which speed and convenience is vital, whereas its applications are concerned it comprises low-throughput research experiments and non-batched testing for infectious diseases. According to Dr. Paul Lem, Chief Executive Officer of Spartan: In the same way that mainframe computers gave rise to personal computers, mainframe DNA machines are giving rise to personal DNA analyzers, DNA is in every organism on the planet and there will be major benefits as DNA testing becomes widely available. This Spartan DXTM stands fit against industry-leading real-time PCR machines standards and is also quite attuned with industry-standard consumables that also comprises inexpensive reaction tubes, real-time PCR reagents and kits from leading manufacturers. Now, you don’t have to stand in hospitals or clinics in long queues to test your DNA as the machine is available on manufacturer’s suggested retail price for USD $14,995. Via: Medgadget