Dr Thomas Force, who teaches medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, has revealed that the cancer-fighting drug, Gleevec can also be a cause of heart failure in leukemia patients under treatment. Force urged the doctors to be aware of the fact that Gleevec could effect the heart. Novartis, on the other hand, supported a detailed research on the matter. Force said that 10 patients taking Gleevec at the University of Texas’ M.D. Anderson Cancer Center have developed the symptoms of heart failure The National Heart, Lung and Blood Institute, the Leukemia and Lymphoma Society, the Finnish Heart Foundation and the Paavo Nurmi Foundation supported the research.
Evidence Based Medicine is the technology that enables the doctors to make precise decision on the medication of their patients rather than just giving a personal opinion. Evidence based medicine is the right care at the right time. Dr. Michael LeFevre, medical director for the Department of Family and Community Medicine at the University of Missouri at Columbia said : The operative words here are ‘good science’. Decisions are based on evidence that includes consistent results from a number of studies … carried out on a large number of patients in a variety of settings. At Esse Health, The doctors examine the patient and feed all the information into the laptop. The computer brings back information on tests that work, tests that don’t work, remedies that work, remedies that are used but don’t work, and even remedies that many doctors didn’t know would work. That is pretty interesting as the patient and the doctor can arrive to a mutual decision. Moreover, Doctors are at ease with this technology while treating their patients.
A study in the August issue of radiology reveals that the symptoms of depression can be reduced by inserting a stent to open a narrowed Carotid artery. Carotid stenosis is caused by the formation of plaque within the carotid artery, which supplies blood to the brain. The build-up of plaque narrows the opening in the artery and can lead to stroke. An interventional radiologist uses an image-guidance system such as computed tomography and a guide wire to reach the site of the narrowing in the artery, expands the artery with a balloon and inserts a stent to hold the artery open. The study’s lead author Wolfgang Mlekusch, M.D., specialist of clinical angiology and internal medicine at Vienna General Hospital and Medical School in Vienna, Austria said: The patients in this study who received carotid stenting showed significantly fewer depressive symptoms than those who did not. Our findings suggest that opening the carotid artery and restoring blood flow to the brain via a minimally invasive technique under local anesthesia is associated with significant reduction in depressive symptoms. We were able to demonstrate a clear neuropsychological benefit to patients after carotid stenting.
Two new studies, one for children and one for adults, at the University of Wisconsin School of Medicine and Public Health Antibiotics, are being carried out to challenge the prevailing recommendation that regular use of antibiotics is not good when person is having asthma attacks. UW is one of eight centers in the nation participating in the Macrolides in Asthma (MIA) trial through the Asthma Clinical Research Network of the National Heart, Lung and Blood Institute. The MIA trial aims to enroll 144 adults (age 18-60) who have moderate to severe asthma symptoms despite use of standard medical therapy. ‘There is emerging evidence from other recent research that, for some patients, adding an antibiotic to standard therapy may improve asthma symptoms considerably,’ says Robert F. Lemanske, Jr., MD, the principal investigator for both UW studies. ‘But the question is far from settled. Even if antibiotics are effective against asthma, the medical community does not yet understand how they might work against the disease–by reducing inflammation, curing a minor infection, or both. These studies are very exciting because they could open up a whole new line of treatment for asthma.’ More than 20 million Americans have been diagnosed with asthma, and the incidence of the disease is growing quickly for reasons that are not well understood. Most patients do well on conventional medication therapy, but some do not respond satisfactorily to current treatments. The current national guidelines for asthma treatment discourage the routine use of antibiotics for asthma. This is mainly, says Lemanske, because of concerns about overuse of antibiotics and the development of resistance with recurrent or chronic use of them. The MARS study seeks to enroll 42 children here (210 nationwide). Potential participants must be between the ages of 6 and 17 years at enrollment and must have moderate to severe asthma requiring significant corticosteroids for control. Following National Institutes of Health guidelines, the goal is to achieve 33 percent minority participation and at least 40 percent female.
A new stethoscope designed by the Acoustical engineer Adrianus Houtsma can help the doctors in the critical situations when life and death hang in balance. This new stethoscope cuts external noises and helps the doctors to diagnose the symptoms and further treatment better. Earlier the external noises especially in the range of 80-85 db used to make the hearing impossible but this new device can operate in a 120 db environment. Houtsma said that further work would focus on making this device more strong and rugged for real life use. He and his colleagues will report there research in the meeting of the Acoustical Society of America and the Acoustical Society of Japan in Honolulu on December 2.